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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Gil Y Melmed: Targeting IL-23 in Crohn’s Disease

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Published Online: Apr 30th 2021

Our Expert Faculty member, Dr Gil Y Melmed (Cedars-Sinai Medical Center, Los Angeles, CA, US), spoke with touchIMMUNOLOGY around the rationale for targeting IL-23 in the treatment of Crohn’s disease and the clinical development of risankizumab.

Questions

  1. What are the limitations of current biologic drugs in the treatment of patients with Crohn’s disease? (0:10)
  2. What is the rationale for targeting IL-23 in Crohn’s disease? (1:03)
  3. Could you give us a brief overview of the clinical development of risankizumab? (2:55)

Disclosures: Gil Y Melmed has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media.

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