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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Andrea Rubbert-Roth, EULAR 2021: The Phase 3 SELECT-CHOICE Study

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Published Online: Jul 23rd 2021

It was a pleasure to meet with Prof. Andrea Rubbert-Roth (Kantonsspital St Gallen, St Gallen, Switzerland) to discuss the comparative efficacy of upadacitinib and abatacept in patients with rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs.

The abstract ‘Clinical responses to upadacitinib or abatacept in patients with rheumatoid arthritis by type of prior biologic disease-modifying antirheumatic drug: Data from the phase 3 SELECT-CHOICE study.‘ was presented at the European Congress of Rheumatology 2021, 2-5 June 2021.

Questions

  1. What did the SELECT-CHOICE study show us in terms of the comparative efficacy of upadacitinib and abatacept in patients with rheumatoid arthritis with inadequate response or intolerance to biologic disease-modifying antirheumatic drugs? (0:22)
  2. What were the objectives of the analysis you are presenting? (1:09)
  3. What were the findings of this analysis? (1:55)
  4. What were the limitations of the analysis? (3:42)
  5. How will these findings impact the future use of JAK inhibitors in routine clinical practice? (4:30)

Disclosures: Andrea Rubbert-Roth discloses receiving honoraria for lectures and consultations from Abbvie, UCB, Gilead, Lilly, Pfizer, MSD, Sanofi, Roche and BMS.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of EULAR 2021 (Virtual).

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