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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Stefan Schreiber, ECCO-IBD 2022: Filgotinib in Ulcerative Colitis: A Post Hoc Analysis of the SELECTION Trial

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Published Online: Mar 25th 2022

We were delighted to talk to Prof. Stefan Schreiber (University Hospital Schleswig-Holstein, Kiel, Germany) around his post hoc analysis of the SELECTION trial, investigating filgotinib in Ulcerative Colitis.

The abstract ‘Exploring disease control by combining clinical, biological, and health-related quality of life remission with endoscopic improvements among Ulcerative Colitis patients treated with filgotinib: A post-hoc analysis from the SELECTION trial’ (Presentation no. OP07) was presented at the 17th Congress of ECCO, February 16-19, 2022!

Questions

  1. How are therapeutic goals evolving in the management of patients with UC? (0:16)
  2.  Could you give us a brief overview of the SELECTION trial and its findings? (1:21)
  3.  What were the aims of your post-hoc analysis of the SELECTION trial data and  how well was the composite endpoint achieved? (2:19)
  4. What will be the impact of these findings on future clinical trial design? (4:28)

Disclosures: Stefan Schreiber reports personal fees from Abbvie, Amgen, Arena, BMS, Biogen, Celltrion, Celgene, IMAB, Gilead, MSD, Mylan, Pfizer, Fresenius, Janssen, Takeda, Theravance, Provention Bio, Protagonist, Falk, Ferring, UCB, Sandoz/Hexal, Lilly & Galapagos.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the ECCO-IBD virtual meeting 2022.

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