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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Ana Maria Giménez-Arnau, EAACI 2022: Pathology and Unmet Needs in Chronic Spontaneous Urticaria

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Published Online: Jul 13th 2022

It was a pleasure to talk with Prof. Ana Maria Giménez-Arnau (Hospital del Mar. IMIM, Universitat Autònoma de Barcelona, Barcelona, Spain) to discuss the unmet needs in the treatment of chronic spontaneous urticaria and the rationale for investigating remibrutinib in this indication.

The abstract ‘Long-term safety and tolerability of remibrutinib (LOU064) in Phase 2b study in chronic spontaneous urticaria patients.’ was presented at EAACI 2022, 1-3 July, 2022.

Questions

  1. Could you tell us a little about chronic spontaneous urticaria (CSU), its incidence and symptoms? (0:34)
  2. What are the unmet needs in the treatment of CSU? (2:58)
  3. What is remibrutinib and what is the rationale for its use in CSU? (5:32)

Disclosures: Ana Maria Giménez-Arnau discloses consulting for Novartis; receiving grant/ research support from Novartis; serving on advisory boards for Novartis; and receiving honoraria from Novartis.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the EAACI Hybrid Congress 2022.

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