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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Philippe Bégin, AAAAI 2021: PEPITES Trial Results

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Published Online: Mar 3rd 2021

TouchIMMUNOLOGY caught up with Philippe Bégin (CHU Sainte-Justine, Montréal, Canada) to discuss the PEPITES trial results, investigating epicutaneous immunotherapy for peanut allergy in children.

The abstract entitled ‘Reduction in Severity Following 12 Months of Epicutaneous Immunotherapy for Peanut Allergy‘ (ABSTRACT NUMBER: 342) was presented at the American Academy of Allergy, Asthma & Immunology Virtual Annual Meeting, February 26-March 1, 2021.

Questions:

1. What are the goals of peanut allergy immunotherapy, in terms of clinical endpoints and patient/caregiver-reported outcomes? (0:14)

2. What did the PEPITES trial teach us about the clinical utility of epicutaneous immunotherapy for peanut allergy in children? (1:39)

3. What were the aims, design and findings of this study, and what is their significance for clinical practice? (3:15)

Disclosures: Philippe Bégin is the clinical trial investigator for DBV technology products.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AAAAI 2021 (Virtual).

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