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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Marcus Maurer, EAACI 2021: Avapritinib for Advanced Systemic Mastocytosis – The PATHFINDER Study

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Published Online: Sep 3rd 2021

touchIMMUNOLOGY joins Professor Marcus Maurer (Charité – Universitätsmedizin Berlin, Berlin, Germany) at EAACI 2021 to discuss the rationale behind avapritinib for advanced systemic mastocytosis and the results of the PATHFINDER study.

Questions

  1. Could you give us a brief overview of the disease burden of advanced systemic mastocytosis and the unmet needs in its treatment? (0:26)
  2. What was the rationale for investigating avapritinib in the treatment of patients with advanced systemic mastocytosis? (1:04)
  3. Could you tell us a little about the PATHFINDER study and its findings? (1:39)
  4. How clinically meaningful are these benefits? (2:35)

Disclosures: In relation to this video interview, MM has received honoraria for advice as well as institutional research support by Blueprint and Celldex.

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the 2021 EAACI Annual Meeting.

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