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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Sara Anvari, MD, AAAAI: Urticaria and/or Angioedema Events Secondary to mRNA Covid-19 Vaccinations -Updates from a National Case Registry

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Published Online: Mar 17th 2022

It was a pleasure to speak with Dr Sara Anvari (Baylor College of Medicine, Texas Children’s Hospital, TX, USA) about her presentation on the COVID-19 Vaccine Allergy Case Registry, where potential cases of severe hypersensitivity reactions to COVID-19 vaccines were collected. 

The abstract entitled ‘Urticaria and/or angioedema events secondary to mRNA COVID-19 vaccinations -Updates from a national case registry’ (Abstract #L05) was presented at The American Academy of Allergy, Asthma & Immunology (AAAAI), February 25-28, 2022

Questions:

  1. Could you tell us a little about the COVID-19 Vaccine Allergy Case Registry and its aims? (00:22)
  2. What were the findings of the registry study in terms of incidence of urticaria and/or angioedema events following mRNA vaccines for COVID-19? (01:28)    
  3. How severe were these events and how were they treated? (02:16)
  4. What was the conclusion of the investigators regarding the suitability of future vaccine doses in patients who experienced these events? (04:00)
  5. What questions remain unanswered and what future studies are planned? (05:25)

Disclosures: Sara Anvari reports grants from NIH/NIAID (R01 AI135197 and UM2 AI130836) and DBV Technologies, outside the submitted work.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

Filmed in coverage of the virtual AAAAI 2022.

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