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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Kristin Kaasen Jørgensen, ECCO-IBD 2022: Proactive Therapeutic Drug Monitoring in IBD – the NOR-DRUM B Study

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Published Online: Mar 1st 2022

We were delighted to talk with Dr Kristin Kaasen Jørgensen (Akershus University Hospital, Nordbyhagen, Norway) around the NOR-DRUM B study, investigating proactive therapeutic drug monitoring during maintenance therapy with infliximab.

The abstract entitled ‘Proactive Therapeutic Drug Monitoring is superior to standard treatment during maintenance therapy with infliximab; results from a 52-week multicentre randomised trial of 450 patients; the NOR-DRUM B study(Presentation no. OP09) was presented at the 17th Congress of ECCO, February 16-19, 2022!

Questions

  1. What are the current limitations of biologic drugs in IBD? (0:19)
  2. What are the potential benefits and pitfalls of a proactive therapeutic drug monitoring as opposed to a reactive strategy? (1:08)
  3. What were the aims and design of the NOR-DRUM B study? (2:49)
  4. What were the study endpoints and how well were these achieved? (4:24)
  5. What will be the impact of these findings on clinical practice? (5:36)

Disclosures: Kristin Kaasen Jørgensen has received personal fees from Roche, BMS, and Norgine.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the ECCO-IBD virtual 2022.

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