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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Stefan Schreiber, ECCO 2021: Risankizumab – an Induction Therapy for Crohn’s Disease

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Published Online: Aug 26th 2021

We were delighted to catch up with Professor Stefan Schreiber (University Hospital Schleswig-Holstein, Kiel, Germany) to discuss the results from the phase 3 ADVANCE and MOTIVATE studies, investigating risankizumab as an induction therapy in patients with moderate-to-severe Crohn’s Disease.

The abstract ‘Risankizumab induces early clinical remission and response in patients with Moderate-to-Severe Crohn’s Disease: Results from the phase 3 ADVANCE and MOTIVATE studies‘ (OP26) was presented at the 16th Congress of ECCO, July 2-3 & 8-10, 2021, Virtual.

Questions

  1. What is the rationale for the use of risankizumab as an induction therapy in patients with moderate-to-severe Crohn’s Disease (CD)? (0:15)
  2. Could you give us a brief overview of the ADVANCE and MOTIVATE studies, and what were the efficacy, safety and tolerability findings? (2:22)

Disclosures: Stefan Schreiber reports personal fees from Abbvie, Arena, BMS, Biogen, Celltrion, Celgene, IMAB, Gilead, MSD, Mylan, Pfizer, Fresenius, Janssen, Takeda, Theravance, provention Bio, Protagonist, Galapagos and Falk.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ECCO 2021 (Virtual).

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