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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Emanuel Della Torre, EASL ILC 2021: IgG4-related Systemic Disease Treatment

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Published Online: Jul 13th 2021

touchIMMUNOLOGY caught up with Dr Emanuel Della Torre (Università Vita-Salute San Raffaele Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, Ospedale San Raffael, Milan, Italy) to discuss the current and future treatment of immunoglobulin G4-related (IgG4) diseases.

His presentation entitled ‘Management: current therapy of IgG4-related systemic disease and what is on the horizon‘ was given at EASL ILC 2021, 23-26 June.

Questions

  1. What factors should be considered when treating patients with IgG4-mediated systemic disease? (0:18)
  2. How common is relapse following glucocorticoid treatment and what are the predictors of relapse? (1:39)
  3. What are the indications for and treatment goals of immunosuppressive treatment? (2:26)
  4. What have we learned about the clinical utility of mycophenolate mofetil and B-cell targeted therapy in this treatment setting? (4:06)
  5. What novel therapeutic approaches are on the horizon? (5:31)

Disclosures: Dr Emanuel Della Torre has nothing to disclose in relation to this video interview.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Gina Furnival.

Filmed in coverage of the EASL ILC 2021, 23-26 June.

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