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From advances in targeted therapies to the integration of AI and steps towards precision medicine, 2024 brought many exciting developments in the field. With 2025 now unfolding, many of these are likely to continue gaining momentum and potentially redefine patient care. In this latest edition of touchREVIEWS in RMD, we’re excited to present a collection […]

Gerd R. Burmester, ACR 2021: Long-term Sarilumab Treatment for Active Rheumatoid Arthritis

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Published Online: Nov 10th 2021

We were delighted to speak with Professor Gerd R. Burmester (Charité – Universitätsmedizin Berlin, Berlin, Germany) around the open label extension studies of sarilumab for the treatment of active rheumatoid arthritis (EXTEND: NCT01146652 and MONARCH: NCT02332590).

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

The abstract ‘Safety and Efficacy of Long-term Sarilumab Treatment in Patients with Active Rheumatoid Arthritis: EXTEND and MONARCH Open Label Extension Studies.‘ (ABSTRACT NUMBER: 1690) was presented at the ACR Convergence, 3-9 November 2021.

Questions

  1. In which patients with rheumatoid arthritis (RA) is sarilumab indicated? (0:15)
  2. What were the aims and design of the analysis of the EXTEND and MONARCH studies? (0:41)
  3. What were the efficacy and safety findings of this analysis? (1:41)
  4. How did these findings compare with other studies? (2:48)
  5. What can we conclude about the long-term efficacy and safety of sarilumab in RA and what questions remain unanswered? (3:20)

Disclosures: Gerd R. Burmester discloses honoraria for lectures and consulting for Sanofi and Roche.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the virtual ACR Convergence 2021.

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