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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Peter C Taylor, ACR 2020 – FINCH Clinical Trial Program

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Published Online: Nov 11th 2020

As always, it was a delight to speak with our Editor-in-Chief, Peter C Taylor (University of Oxford, Oxford, UK). In this interview, we discuss JAK inhibitors and RA-related pain alongside the findings from the FINCH Phase 3 RA clinical trial program of filgotinib. The abstract ‘Effect of Filgotinib on Pain in Patients with Rheumatoid Arthritis: Results from Phase 3 Clinical Trials’ (ABSTRACT NUMBER: 1201) was presented at the virtual ACR Convergence 2020, 5-9 November 2020.

Questions

1. What are the major unmet needs in terms of pain control in the treatment of rheumatoid arthritis? (0:06)

2. What is the rationale for the use of JAK inhibitors in the treatment of rheumatoid arthritis? (1:49)

3. Could you give us a brief overview of the FINCH clinical studies and the findings? (3.32)

4. Could you tell us about the post-hoc analysis of the FINCH studies data? (4:22)

5. How do you think these findings could impact clinical practice? (10:36)

Disclosures: Peter C Taylor reports receiving: Research grants from Celgene, Galapagos, Gilead and Lilly; and consultation fees from AbbVie, BMS, Biogen, Fresenius, Galapagos, Gilead, GlaxoSmithKline, Janssen, Lilly, Nordic Pharma, Pfizer, Roche, Sanofi, and UCB.

Support: Interview and filming supported by Touch Medical Media Ltd.

Filmed in coverage of virtual ACR Convergence 2020.

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