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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Rene Westhovens, ACR 2020 – Results from the FINCH 3 Study (Part 2)

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Published Online: Nov 20th 2020

Following his presentation at ACR 2020, Rene Westhovens talked to us about the 52 week results of the FINCH 3 study. The phase 3 study evaluated the efficacy and safety of filgotinib in methotrexate-naïve patients with rheumatoid arthritis (Clinical Trial Identifier: NCT02886728). The abstract ‘Efficacy and Safety of Filgotinib in Methotrexate-Naïve Patients with Rheumatoid Arthritis: 52-Week Results’ (ABSTRACT NUMBER: 0217) was presented at the virtual ACR Convergence 2020, 5-9 November 2020.

Questions

  1. What were the 52-week findings from the FINCH-3 study? (0:39)
  2. What are your thoughts on the FDA rejecting filgotinib for moderate to severe active RA due to testicular toxicity? (4:00)
  3. If approved, where will filgotinib fit into the treatment paradigm for RA? (6:28)

Disclosures: Principal Investigator and Advisor for Celltrion and also Gilead/Galapagos

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the ACR 2020 Annual Meeting (Virtual).

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