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Hypermobility spectrum disorders (HSDs) refer to a group of conditions characterized by an increased range of motion in joints beyond the normal limits, often due to connective tissue laxity. More stringent criteria are applied in the diagnosis of hypermobile Ehlers–Danlos syndrome (hEDS).1 HSDs are increasingly well-recognized among young people and frequently attract referrals to healthcare providers […]

Atul Deodhar, ACR 2021: Bimekizumab Long-term HRQoL data in Ankylosing Spondylitis

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Published Online: Dec 14th 2021

Prof. Atul Deodhar (Oregon Health & Science University, Portland, OR, USA) kindly took the time to discuss the 3-yr interim health-related quality of life (HRQoL) data from the phase 2b BE AGILE study (NCT02963506) and its open-label extension (NCT03355573) investigating bimekizumab in ankylosing spondylitis.

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

The abstract entitled ‘Bimekizumab Shows Sustained and Meaningful Long-Term Improvements in Health-Related Quality of Life in Ankylosing Spondylitis: Interim Results After 3 Years of Treatment in an Ongoing Phase 2b Study’ (ABSTRACT NUMBER: 0922) was presented at the ACR Convergence, 5-9 November 2021.

Questions

  1. Could you tell us a little about bimekizumab and its mechanism of action? (0:14)
  2. What have previous phase 2 studies with bimekizumab demonstrated and what were the aims of the current analysis? (0:48)
  3. Could you tell us about the design of the current analysis and the overall findings? (1:33)

Disclosures: Prof. Atul Deodhar has been a consultant/ advisory board member for AbbVie, Amgen, Aurinia, Boehringer Ingelheim, Bristol Myers Squibb, Celgene, Eli Lilly, Glaxo Smith & Kline, Janssen, Moonlake, Novartis, Pfizer and UCB, and received research grants from AbbVie, Eli Lilly, Glaxo Smith & Kline, Novartis, Pfizer and UCB.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Gina Furnival.

Filmed in coverage of virtual ACR Convergence 2021.

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