Digestive Disorders

Each year, the United European Gastroenterology (UEG) organisation awards a prestigious €50,000 Research Prize to recognise excellence in basic science, translational, or clinical research. This award supports future innovative scientific projects from inception to completion, emphasizing their transformative potential to enhance patient care. This year’s recipient, Dr. Enrique de-Madaria, Gastroenterologist and Coordinator of the Biliary-Pancreatic Unit at Dr. Balmis Hospital in Alicante, Spain, has been honoured for his groundbreaking work in fluid resuscitation for acute pancreatitis. Over the past decade, his multicentre studies—bolstered by national and international collaborations—have redefined clinical practice and established new standards of care.

IgG4-RD is a rare, chronic, relapsing condition characterized by fibroinflammatory lesions rich in CD19+ B cells, which can damage multiple organ systems and lead to organ failure.1 With no approved therapies, glucocorticoids are the primary treatment, but their long-term use is associated with adverse effects and inadequate disease control.1

New research presented at UEG Week 2024 has introduced a strategy that could considerably reduce the need for insulin therapy in patients with type 2 diabetes (T2D).¹ The study investigated a novel approach combining ReCET (Re-Cellularization via Electroporation Therapy) with the GLP-1 RA, semaglutide. Remarkably, 86% of participants enrolled in the study were able to […]

Eosinophilic oesophagitis (EoE) is a chronic, immune-mediated inflammatory disease of the oesophagus that is progressive in nature and increasingly prevalent worldwide.1  The condition is driven by antigen-induced type 2 inflammation, leading to the infiltration of eosinophils, which causes esophageal dysfunction and related symptoms. For some with EoE, current treatments are insufficient to control the condition, […]