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Rare diseases (RDs) are generally defined as affecting one in every 20,000, with 5,000–8,000 distinct conditions affecting millions globally.1 Diagnostic complexity and lack of awareness often lead to delayed diagnosis and treatment, averaging 5.6–7.6 years with poor outcomes.2 Centralizing expertise through specialized centres can improve diagnosis and outcomes, advance research and support patient advocacy. Global initiatives, such as those […]

Primary Immunodeficiencies

An Introduction to Primary Immunodeficiencies

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July delivered a broad range of important updates in immunology, spanning regulatory approvals, new therapeutic formulations, and key clinical trial results across autoimmune, inflammatory, and rare diseases. This monthly roundup highlights the most significant developments, including first-in-class oral therapies, expanded paediatric indications, and both positive and negative late-phase trial outcomes.

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Watch consultant immunologists Dr Dalm and Dr Chandra outline what APDS is, the common features of this disease and option for diagnosis, treatment and management.

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Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.

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What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career doctors ready to think beyond the bedside and explore the business of medicine.

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In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.

Coverage from: AAAAI Highlights

We were delighted to meet with Kelli Williams (Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA) to discuss the current hot topics in pediatric immunodeficiency. The talk entitled 'Hot Topics in Pediatric Immunodeficiency' was presented as part ...

Coverage from: AAAAI Highlights

It was a pleasure to speak with Bob Geng (University of California, San Diego, CA, USA) to discuss study results investigating subcutaneous human immunoglobulin 16.5% in patients with primary immunodeficiencies. The abstract entitled 'Long-Term Safety, Efficacy, and Tolerability of Subcutaneous Human ...

Coverage from: AAAAI Highlights

It was a pleasure to speak with Bob Geng (University of California, San Diego, CA, USA) to give us an overview of immunoglobulin replacement therapy, and subcutaneous human IgG 16.5% in patients with immunodeficiencies. The abstract entitled 'Long-Term Safety, Efficacy, and ...

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