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    • Rheumatoid Arthritis

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    Rheumatoid Arthritis

    Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterised by synovial joint inflammation leading to cartilage destruction and bone erosion. Early diagnosis and treatment is essential to minimise the risk of future joint damage and disability. Treatment options include conventional disease-modifying anti-rheumatic drugs (DMARDS) such as methotrexate, and biological therapies including tumour necrosis factor (TNF) inhibitors and interleukin-6 antagonists. However, some patients fail to respond to biologic therapies. An exciting new development is small molecule DMARDs targeting intracellular signalling pathways, which include Janus kinase (JAK) inhibitors. Other recent developments include a biologic DMARD that targets and suppresses the inflammatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF).

    Expert video highlights and insights from the conference hub and comprehensive peer-reviewed articles from our journal portfolio provide updates on the changing treatment landscape. To learn more about how the latest developments impact on patient outcomes view our expert-led learning activities.

    Our supporting partners do not constitute an endorsement of the content on this page.

    Rheumatoid Arthritis Content

    Rheumatic Diseases, Rheumatoid Arthritis
    New study reveals elevated cognitive impairment risk in rheumatoid arthritis patients, linked to inflammation and comorbidities

    A new study published in RMD Open has revealed that individuals with rheumatoid arthritis (RA) are significantly more likely to experience cognitive impairment. The study, which involved 70 RA patients and 70 matched healthy controls, showed that 60% of RA patients scored below the threshold for cognitive impairment on the Montreal Cognitive Assessment (MoCA), compared to 40% of the control group. This cognitive decline was most pronounced in visuospatial-executive function, memory and abstraction.

    Psoriatic Arthritis, Rheumatic Diseases, Rheumatoid Arthritis, Sjögren’s Syndrome
    Highlights from EULAR 2024: Advancing rheumatology

    As we have come to expect, EULAR 2024 was a busy and productive meeting, packed with news and lively discussions among rheumatologists. The conference, which took place in Vienna, Austria, highlighted a wealth of innovative research and significant advancements in rheumatology. From new treatments to groundbreaking clinical studies, the abstracts presented this year showcased exciting […]

    Rheumatoid Arthritis
    Developed by Touch
    Key data on pain and prognosis: Clinical insights and implications
    Peter C Taylor Watch Time: 18 mins

    Beginning with the Canadian Early Arthritis Cohort (CATCH) we explore non-articular pain in patients with early RA and discuss how the findings could support a link between disease activity and non-articular pain, as well as confirm the need to intervene. Staying in early RA, we then discuss the two-year data PRAIRI trial data and what they demonstrated in terms of the impact of rituximab on the quality of life of patients with pre-RA. 

    Rheumatic Diseases, Rheumatoid Arthritis
    Developed by Touch
    NRAS’s mission and impact on the RA community: Ailsa Bosworth, National Rheumatoid Arthritis Society

    We had the pleasure of talking with Ailsa Bosworth, a patient advocate for rheumatoid arthritis (RA), and Founder and National Patient Champion for the National Rheumatoid Arthritis Society (NRAS), UK. In this interview, Ailsa explores NRAS’s profound impact on the RA community, and her role and experiences within the NRAS, and pivotal contributions to pioneering […]

    Rheumatic Diseases, Rheumatoid Arthritis
    Developed by Touch
    A patient’s perspective – journey to diagnosis of seronegative rheumatoid arthritis: Ailsa Bosworth, National Rheumatoid Arthritis Society
    Watch Time: 9 mins

    We are joined by Ailsa Bosworth, Founder and National Patient Champion for the National Rheumatoid Arthritis Society (NRAS), UK. Ailsa Bosworth is a patient advocate for rheumatoid arthritis (RA) and joins us in this interview to discuss her personal journal to, and following, diagnosis of seronegative RA and the challenges she has faced along the […]

    Rheumatoid Arthritis
    Multiomics Studies in Rheumatoid Arthritis: The Search for the Holy Grail of Predicting Treatment Response
    Stephanie F Ling, Darren Plant

    touchREVIEWS in RMD. 2024;3(1):10–12

    Although biological disease-modifying antirheumatic drugs (bDMARDs) are significantly cheaper now that biosimilar agents are available, they still represent a significant cost to health services worldwide, particularly since their prescription has only increased since the thresholds for commencing this treatment have been lowered. For example, in 2017/8, the total cost of adalimumab to the NHS in England […]

    Rheumatoid Arthritis
    Foreword – touchREVIEWS in RMD, Volume 2, Issue 1, 2023

    Welcome to the latest issue of touchREVIEWS in RMD, which aims to provide healthcare professionals with a wide range of topical articles in the field of rheumatic and musculoskeletal diseases (RMDs). We begin with an informative practice pearl from Sun and Pope. This paper examines the potential solutions to integrate into clinical practice that may […]

    Rheumatoid Arthritis
    Strategies to Improve Adherence in Patients with Rheumatoid Arthritis
    Margaret Man-Ger Sun, Janet E Pope

    touchREVIEWS in RMD. 2023;2(1):2–3 DOI: https://doi.org/10.17925/RMD.2023.2.1.2

    Rheumatoid arthritis (RA) is a chronic, autoimmune, inflammatory disease that affects synovial joints but may be accompanied by systemic and extra-articular manifestations.1,2 Patients with RA are associated with a higher mortality rate compared with the general population and with increased socioeconomic burden from lost productivity at work, disability and cost of treatment.3 Therefore, appropriate disease management is […]

    Rheumatoid Arthritis
    Developed by Touch
    Peter Taylor, EULAR 2023: Current perspectives on the selectivity and safety of JAK inhibitors to target the pathophysiology of rheumatoid arthritis
    Watch Time: 9 mins

    Janus kinase inhibitors (JAKis) are an emerging new class of disease-modifying medication for the treatment of rheumatoid arthritis (RA). touchIMMUNOLOGY spoke with our Editor-in-Chief Prof Peter Taylor (University of Oxford, UK) to discuss the latest insights into the use, selectivity and safety of JAK inhibitors, and how they are used to target the pathophysiology of […]

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