Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterised by synovial joint inflammation leading to cartilage destruction and bone erosion. Early diagnosis and treatment is essential to minimise the risk of future joint damage and disability. Treatment options include conventional disease-modifying anti-rheumatic drugs (DMARDS) such as methotrexate, and biological therapies including tumour necrosis factor (TNF) inhibitors and interleukin-6 antagonists. However, some patients fail to respond to biologic therapies. An exciting new development is small molecule DMARDs targeting intracellular signalling pathways, which include Janus kinase (JAK) inhibitors. Other recent developments include a biologic DMARD that targets and suppresses the inflammatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF).
Expert video highlights and insights from the conference hub and comprehensive peer-reviewed articles from our journal portfolio provide updates on the changing treatment landscape. To learn more about how the latest developments impact on patient outcomes view our expert-led learning activities.
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Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.
touchREVIEWS in RMD is proud to welcome Dr Vinod Ravindran to our editorial board. With a distinguished background in clinical rheumatology, medical education, and research, Dr Ravindran is widely recognized for his contributions to advancing care and understanding in the field.
In this episode, we explore the future of continuing medical education (CME) with the team behind touchIME. Hannah Fisher and Matthew Goodwin share insights into global and US trends, the importance of patient inclusivity and how educational outcomes are evolving to better measure the direct impact of learning on clinical practice and patient care.
In this edition of our Future Leaders series, we speak with Dr. Santhanam Sham, a rising star in rheumatology. As a Senior Consultant at Kauvery Hospitals, Chennai, Dr. Sham is dedicated to advancing research on autoimmune diseases like SLE and vasculitis, while also fostering patient-centric care and embracing cutting-edge medical technologies.
From advances in targeted therapies to the integration of AI and steps towards precision medicine, 2024 brought many exciting developments in the field. With 2025 now unfolding, many of these are likely to continue gaining momentum and potentially redefine patient care. In ...
Rheumatoid arthritis (RA) is one of the most challenging autoimmune diseases. Early, targeted and effective therapy is crucial for achieving remission and preventing long-term joint destruction. Over the past two decades, tumour necrosis factor (TNF) inhibitors (TNFi) have been the ...
A new study published in RMD Open has revealed that individuals with rheumatoid arthritis (RA) are significantly more likely to experience cognitive impairment. The study, which involved 70 RA patients and 70 matched healthy controls, showed that 60% of RA patients scored below the threshold for cognitive impairment on the Montreal Cognitive Assessment (MoCA), compared to 40% of the control group. This cognitive decline was most pronounced in visuospatial-executive function, memory and abstraction.
As we have come to expect, EULAR 2024 was a busy and productive meeting, packed with news and lively discussions among rheumatologists. The conference, which took place in Vienna, Austria, highlighted a wealth of innovative research and significant advancements in rheumatology. ...
Although biological disease-modifying antirheumatic drugs (bDMARDs) are significantly cheaper now that biosimilar agents are available, they still represent a significant cost to health services worldwide, particularly since their prescription has only increased since the thresholds for commencing this treatment have ...
Rheumatoid arthritis (RA) is a chronic, autoimmune, inflammatory disease that affects synovial joints but may be accompanied by systemic and extra-articular manifestations.1,2Â Patients with RA are associated with a higher mortality rate compared with the general population and with increased ...
Standardization of the assessment of disease activity in patients with rheumatoid arthritis (RA) has made a big difference in the comparability of clinical trials and in treatment processes in clinical practice.1–3 Disease activity is the underlying driver for radiographic progression, ...
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