Vasculitis encompasses a diverse group of rare disorders linked by inflammation of blood vessel walls, which may result in organ failure or death. Vasculitis is categorized by size of the predominant vessel involved and includes small-, medium-, and large-vessel vasculitis. The most common forms are giant cell arteritis and polymyalgia rheumatica. Vasculitis may be primary, with no known cause, or secondary to infection, drugs, toxins, inflammatory disorder or cancer. They have a broad range of clinical presentations that can be systemic or organ-specific, and are often similar to more common diseases, resulting in diagnostic delay and poor outcomes. Treatment options include corticosteroids, methotrexate, azathioprine, mycophenolate, cyclophosphamide, tocilizumab and rituximab.
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This corrects the article: “Gheriani GA, Tuetken R and Lenert P. Lane–Hamilton Syndrome: A Vasculitis Mimic Presenting with Diffuse Alveolar Haemorrhage and Positive ANCA Testing. touchREVIEWS in RMD. 2024;3(1):37–42” The patient consent statement was added incorrectly due to an editorial ...
Diffuse alveolar haemorrhage (DAH) is associated with high morbidity and mortality. The causes of DAH are diverse, and include rheumatologic conditions such as granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), Systemic lupus erythematosus (SLE) and Goodpasture’s syndrome (Table 1). Rheumatologists ...
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) represents a spectrum of disorders primarily affecting the small blood vessels in various organs. It often affects the kidneys, causing rapidly progressive renal failure due to necrotizing crescentic glomerulonephritis. Another major cause of ...
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