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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Catherine Sims, ACR 2022: Impact of the HOP-STEP intervention in women with systemic lupus erythematosus

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Published Online: Nov 15th 2022

In women with systemic lupus erythematosus (SLE), ill-timed pregnancies can cause complications related to teratogen use and SLE activity. In this touchIMMUNOLOGY interview we spoke with Dr. Catherine Sims (Duke University, Durham, NC, USA) around her study implementing the HOP-STEP intervention to promote well-timed pregnancies in women with SLE, and the impact of the HOP-STEP pregnancy planning discussions on pregnancy complications.

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

The abstract The Impact of Pregnancy Planning and Medical Readiness on Reproductive Outcomes in Women with SLE. (Abstract number: 0946) was presented at the ACR Convergence, November 10–14, 2022.

Questions

  1. What are the challenges of the current recommendations of the ACR Reproductive Health Guidelines for women with systemic lupus erythematosus (SLE) in planning pregnancy? (0:14)
  2. What is the HOP-STEP intervention? (1:27)
  3. What were the aims and design of your SLE registry study? (3:06)
  4. What was the impact of the HOP-STEP pregnancy planning discussions on pregnancy complications? (4:00)
  5. What are the key take-home messages of this study? (4:59)

Disclosures: Catherine Sims discloses grant/research support from UCB.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Atiya Henry.

Filmed in coverage of the ACR Convergence 2022.

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