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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Kathryn Torok, ACR 2021: Preliminary Data from Autologous Stem Cell Transplant in Juvenile-Onset Systemic Sclerosis

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Published Online: Nov 11th 2021

It was an absolute pleasure to speak with Professor Kathryn Torok (UPMC & University of Pittsburgh Scleroderma Center, University of Pittsburgh, Pittsburgh, PA, USA) around the initial safety and clinical responses of patients with juvenile-onset systemic sclerosis treated with CD34-selected peripheral blood ASCT (NCT03630211).

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

Questions

  1. What have been the initial safety and clinical responses of patients undergoing this procedure? (0:19)
  2. Based on these findings, how should ASCT eligibility criteria be expanded? (3:43)
  3. What future studies are planned? (6:53)

Disclosures: Kathryn Torok has nothing to disclose in relation to this video.

Correspondence: Kathryn Torok, MD, Associate Professor of Pediatrics, Division of Pediatric Rheumatology, UPMC & University of Pittsburgh Scleroderma Center, University of Pittsburgh |UPMC Children’s Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA 15224, Tel: (412) 692-5081 | Fax: (412) 692-5054 | kathryn.torok@chp.edu

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the virtual ACR Convergence 2021.

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