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Rare diseases (RDs) are generally defined as affecting one in every 20,000, with 5,000–8,000 distinct conditions affecting millions globally.1 Diagnostic complexity and lack of awareness often lead to delayed diagnosis and treatment, averaging 5.6–7.6 years with poor outcomes.2 Centralizing expertise through specialized centres can improve diagnosis and outcomes, advance research and support patient advocacy. Global initiatives, such as those […]

Bhaskar Dasgupta, ACR 2022: A validation study of the Southend pre-test probability score

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Published Online: Nov 15th 2022

The southend pre-test probability score (SPTPS) was recently developed to estimate the probability of giant cell arteritis (GCA) based on symptoms, signs and lab findings. In this interview with Prof. Bhaskar Dasgupta (Southend University Hospital NHS Foundation Trust, Southend-on-Sea, UK) we discuss the validation study of SPTPS and how effective the score was in assessing the clinical probability of GCA among suspected new cases.

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

The abstract ‘Probability-based Diagnostic Algorithm in Suspected Giant Cell Arteritis: A Prospective, Multicentre Validity Data from HAS GCA Study‘ (Abstract number: 1620) was presented at the ACR Convergence, November 10–14, 2022.

Questions

  1. Can you give us a brief overview of the Southend pre-test probability score (SPTPS)? (0:05)
  2. What was the methodology of your validation study of SPTPS? (1:55)
  3. How effective was the SPTPS in assessing the clinical probability of GCA among people with suspected new onset GCA? (5:44)

Disclosures: Bhaskar Dasgupta discloses consulting for Sanofi; receiving grant/ research support from Sanofi; and receiving honoraria from Sanofi.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Gina Furnival.

Filmed in coverage of the ACR Convergence 2022.

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