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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Laure Gossec, ACR 2020 – Results from the BE ACTIVE Study

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Published Online: Nov 13th 2020

We were delighted to speak to Laure Gossec (Sorbonne Université and Pitié-Salpétrière Hospital, Paris, France) about the 48-week results of the BE ACTIVE phase 2b study of bimekizumab in psoriatic arthritis (Clinical Trial Identifier: NCT02969525). The abstract ‘Bimekizumab Improves Patient-Reported Outcomes in Psoriatic Arthritis: 48-Week Results from a Phase 2b Study and Association Between Patient-Reported Outcomes and Disease Activity‘ (ABSTRACT NUMBER: 0356) was presented at the virtual ACR Convergence 2020, 5-9 November 2020.

Questions

  1. Could you tell us a little about bimekizumab and its mechanism of action? (0:15)
  2. Why are patient-reported outcomes (PROs) important and what are the most useful PROs in psoriatic arthritis? (0:37)
  3. Could you tell us a little about the BE ACTIVE study? (1:25)
  4. What were the major findings of the BE ACTIVE study? (2:09)
  5. How well did the PROs correlate with disease activity, and what are the implications of these findings for clinical practice? (3:07)

Disclosures: Research grants: Amgen, Galapagos, Janssen, Lilly, Pfizer, Sandoz, Sanofi; consulting fees: AbbVie, Amgen, BMS, Biogen, Celgene, Gilead, Janssen, Lilly, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis, UCB.

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the ACR Convergence 2020 (Virtual).

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