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The use of immune checkpoint inhibitors (ICIs) in treating cancer has greatly improved survival outcomes, particularly in patients with advanced disease for whom successful treatment options have previously been limited. For example, in patients with metastatic melanoma, the median survival time has improved from just 6 months to approximately 6 years with the use of […]

Laure Gossec, ACR 2021: Long-term Impact of Bimekizumab on Patient-reported Outcomes in PsA

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Published Online: Nov 11th 2021

Prof. Laure Gossec (Sorbonne Universite, Paris, France) kindly took the time to speak with touchIMMUNOLOGY about the long-term impact of the IgG1 inhibitor, bimekizumab, on patient-reported outcomes from the phase 2b BE ACTIVE study (NCT02969525) and its open-label extension (NCT03347110).

This information is brought to you by Touch Medical Media and is not sponsored by, nor a part of, the American College of Rheumatology.

The poster entitled ‘Sustained Improvement in Physical Function, Disease Impact and Health­-Related Quality of Life in Patients with Psoriatic Arthritis Treated with Bimekizumab: 3-Year Results from a Phase 2b Open-Label Extension Study’ (ABSTRACT NUMBER: 1350) was presented at the ACR Convergence, 5-9 November 2021.

Questions

  1. How important are patient-reported outcomes as a clinical endpoint in psoriatic arthritis (PsA)? (0:10)
  2. What were the aims of the current analysis of the BE ACTIVE and OLE study data? (0:51)
  3. What was the impact of bimekizumab on patient-reported outcomes? (1:28)

Disclosures: Prof. Laure Gossec has received grant/research support from ​Galapagos, Sandoz, Sanofi, Amgen, Eli Lilly, Janssen and Pfizer; and acted as a consultant for AbbVie, Amgen, Bristol Myers Squibb, Biogen, Celgene, Eli Lilly, Gilead, Janssen, Novartis, Pfizer, Samsung Bioepis, Sanofi-Aventis and UCB.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Gina Furnival.

Filmed in coverage of virtual ACR Convergence 2021.

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