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Samantha Cooray, Alexander Deng, Tim Dong

There is much excitement about the deployment of artificial intelligence (AI) in healthcare, and the musculoskeletal field is no exception. In this article, we introduce some of the latest developments relating to osteoarthritis (OA), osteoporosis, rheumatoid arthritis (RA) (as an example of inflammatory arthritis), connective tissue disease (CTD), Ehlers–Danlos syndrome (EDS) and musculoskeletal surgical interventions. […]

Luis Puente-Maestu, ERS 2021: The Phase 3 Study of MV130

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Published Online: Oct 5th 2021

It was a pleasure to meet with Dr Luis Puente-Maestu (Hospital General Universitario Gregorio Marañón, Madrid, Spain) to explore the efficacy and safety findings from the phase 3 study of MV130 for the prevention of COPD exacerbations.

The abstract ‘Randomized, double-blind, placebo-controlled, phase III clinical trial with MV130, a sublingual bacterial immunotherapy to prevent COPD exacerbations.’ (Presentation ID 207) was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. What were the aims, design, and clinical outcome measures of the phase 3 study? (0:38)
  2. What were the efficacy and safety findings from the study? (2:51)
  3. What are the implications of these findings for patients with COPD? (6:05)

Disclosures: Luis Puente-Maestu has received personally or for his department grants, funds, fees or equipment from GSK, Boheringer, Astra-Zeneca, MSD, Esteve, Chiesi, Menarini, Boston Scientific and air liquide.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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