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At the American College of Rheumatology (ACR) Convergence 2025, Dr. Pamela Weiss delivered a focused presentation on the diagnosis and management of axial juvenile spondyloarthritis (axJSpA), highlighting key distinctions and overlaps with adult-onset disease. This targeted article synthesizes the principal objectives and takeaways from that session: identification of the characteristic clinical features of axJSpA, the […]

Luis Puente-Maestu, ERS 2021: MV130 Immunotherapy to Prevent COPD Exacerbations

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Published Online: Oct 5th 2021

It was great to talk with Dr Luis Puente-Maestu (Hospital General Universitario Gregorio Marañón, Madrid, Spain) around the abstract ‘Randomized, double-blind, placebo-controlled, phase III clinical trial with MV130, a sublingual bacterial immunotherapy to prevent COPD exacerbations.’ (Presentation ID 207), which was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. What is known about bacterial immunostimulants for the treatment of COPD exacerbations? (0:38)
  2. What is the mechanism of action of MV130 and what was the rationale for its use in preventing COPD exacerbations? (2:13)

Disclosures: Luis Puente-Maestu has received personally or for his department grants, funds, fees or equipment from GSK, Boheringer, Astra-Zeneca, MSD, Esteve, Chiesi, Menarini, Boston Scientific and air liquide.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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