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Jérôme Avouac

Dear readers, It is a great pleasure to take on the role of Editor-in-Chief of touchREVIEWS in RMD, and I am grateful for the opportunity to introduce myself and to share my vision for the journal. I am a Professor of Rheumatology at Université Paris Cité and a consultant rheumatologist at Hôpital Cochin (AP-HP) in […]

Hyun C Chung, ASCO GI 2021: Lenvatinib plus Pembrolizumab in Patients with Advanced Solid Tumours

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Published Online: Feb 1st 2021

We were delighted to talk to Hyun C Chung (Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea) about the combination of lenvatinib plus pembrolizumab in the treatment of patients with advanced solid tumours (Clinical Trial Identifier: NCT03797326).

The abstract ‘LEAP-005: A phase II multicohort study of lenvatinib plus pembrolizumab in patients with previously treated selected solid tumors: Results from the gastric cancer cohort.’ (ABSTRACT NUMBER: 230) was presented at the virtual ASCO Gastrointestinal Cancers Symposium 2021, 15-17 January, 2021.

Questions

  1. What is the rationale for the use of lenvatinib plus pembrolizumab in patients with advanced solid tumours? (0:05)
  2. Which patients are most likely to respond to this combination? (1:06)

Disclosures: Hyun C Chung discloses Grant/Research Support from Lilly, GSK, MSD, Merck-Serono, BMS/Ono, Taiho, Amgen, Beigene, Incyte and Zymework; Honoraria from Merck-Serono and Lilly; Consultation for Taiho, Celltrion, MSD, Lilly, BMS, Merck-Serono, Gloria, Beigene, Amgen and Zymework.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of ASCO GI 2021 (Virtual).

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