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At the American College of Rheumatology (ACR) Convergence 2025, Dr. Pamela Weiss delivered a focused presentation on the diagnosis and management of axial juvenile spondyloarthritis (axJSpA), highlighting key distinctions and overlaps with adult-onset disease. This targeted article synthesizes the principal objectives and takeaways from that session: identification of the characteristic clinical features of axJSpA, the […]

Bob Geng, AAAAI 2021: Immunoglobulin Replacement Therapy (Part 1)

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Published Online: Mar 2nd 2021

It was a pleasure to speak with Bob Geng (University of California, San Diego, CA, USA) to give us an overview of immunoglobulin replacement therapy, and subcutaneous human IgG 16.5% in patients with immunodeficiencies.

The abstract entitled ‘Long-Term Safety, Efficacy, and Tolerability of Subcutaneous Human Immunoglobulin 16.5% in Patients with Primary Immunodeficiencies‘ (ABSTRACT NUMBER: 238) was presented at the American Academy of Allergy, Asthma & Immunology Virtual Annual Meeting, February 26-March 1, 2021.

Part 2 of our discussion can be viewed here.

Questions:

1. Could you give us a brief overview of immunoglobulin replacement therapy in patients with primary immunodeficiencies? (0:18)

2. What are the advantages and limitations of subcutaneous human IgG 16.5% compared with other IgG formulations? (1:48)

Disclosures: Consultant and speaker for Takeda and Grifols; consultant for Koru and Kedrion; provided clinical trial support for Octapharma.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AAAAI 2021 (Virtual).

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